• Adipokines and inflammation markers and risk of differentiated thyroid carcinoma: The EPIC study 

      Dossus, Laure; Franceschi, Silvia; Biessy, Carine; Navionis, Anne-Sophie; Travis, Ruth C.; Weiderpass, Elisabete; Scalbert, Augustin; Romieu, Isabelle; Tjønneland, Anne; Olsen, Anja; Overvad, Kim; Boutron-Ruault, Marie-Christine; Bonnet, Fabrice; Fournier, Agnès; Fortner, Renée Turzanski; Kaaks, Rudolf; Aleksandrova, Krasimira; Trichopoulou, Antonia; La Vecchia, Carlo; Peppa, Eleni; Tumino, Rosario; Panico, Salavatore; Palli, Domenico; Agnoli, Claudia; Vineis, Paolo; Bueno-de-Mesquita, Hendrik Bastiaan; Peeters, Petra H.; Skeie, Guri; Zamora-Ros, Raul; Chirlaque, María-Dolores; Ardanaz, Eva; Sánchez, Maria-Jose; Quirós, Jose Ramón; Dorronsoro, Miren; Sandström, Maria; Nilsson, Lena Maria; Schmidt, Julie A.; Khaw, Kay-Tee; Tsilidis, Konstantinos K.; Aune, Dagfinn; Riboli, Elio; Rinaldi, Sabina (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-11-23)
      Other than the influence of ionizing radiation and benign thyroid disease, little is known about the risk factors for differentiated thyroid cancer (TC) which is an increasing common cancer worldwide. Consistent evidence shows that body mass is positively associated with TC risk. As excess weight is a state of chronic inflammation, we investigated the relationship between concentrations of leptin, ...
    • Alcohol intake and breast cancer in the European prospective investigation into cancer and nutrition 

      Romieu, Isabelle; Scoccianti, Chiara; Chajès, Véronique; De Batlle, Jordi; Biessy, Carine; Dossus, Laure; Baglietto, Laura; Clavel-Chapelon, Françoise; Overvad, Kim; Olsen, Anja; Tjønneland, Anne; Kaaks, Rudolf; Lukanova, Annekatrin; Boeing, Heiner; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; Palli, Domenico; Sieri, Sabina; Tumino, Rosario; Vineis, Paolo; Panico, Salvatore; Bueno-de-Mesquita, H. Bas; van Gils, Carla H.; Peeters, Petra H.; Lund, Eiliv; Skeie, Guri; Weiderpass, Elisabete; García, José Ramón Quirós; Chirlaque, Maria-Dolores; Ardanaz, Eva; Sánchez, María-José; Duell, Eric J.; Amiano, Pilar; Borgquist, Signe; Wirfält, Elisabet; Hallmans, Göran; Johansson, Ingegerd; Nilsson, Lena Maria; Khaw, Kay-Tee; Wareham, Nick; Key, Timothy J.; Travis, Ruth C.; Murphy, Neil; Wark, Petra A.; Ferrari, Pietro; Riboli, Elio (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-02-09)
      Alcohol intake has been associated to breast cancer in pre and postmenopausal women; however results are inconclusive regarding tumor hormonal receptor status, and potential modifying factors like age at start drinking. Therefore, we investigated the relation between alcohol intake and the risk of breast cancer using prospective observational data from the European Prospective Investigation into ...
    • Biomarkers of folate and vitamin B12 and breast cancer risk: report from the EPIC cohort 

      Matejcic, Marco; De Batlle, Jordi; Ricci, Cristian; Biessy, Carine; Perrier, Flavie; Huybrechts, Inge; Weiderpass, Elisabete; Boutron-Ruault, Marie-Christine; Cadeau, Claire; His, Mathilde; Cox, David G.; Boeing, Heiner; Fortner, Renée Turzanski; Kaaks, Rudolf; Lagiou, Pagona; Trichopoulou, Antonia; Benetou, Vassiliki; Tumino, Rosario; Panico, Salvatore; Sieri, Sabina; Palli, Domenico; Ricceri, Fulvio; Bueno-De-Mesquita, Hendrik Bastiaan; Skeie, Guri; Amiano, Pilar; Sánchez, María-José; Chirlaque, María-Dolores; Barricarte, Aurelio; Quirós, José Ramón; Buckland, Genevieve; van Gils, Carla H.; Peeters, Petra H.; Key, Timothy J.; Riboli, Elio; Gylling, Björn; Zeleniuch-Jacquotte, Anne; Gunter, Mark J.; Romieu, Isabelle; Chajès, Véronique (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-01)
      Epidemiological studies have reported inconsistent findings for the association between B vitamins and breast cancer (BC) risk. We investigated the relationship between biomarkers of folate and vitamin B12 and the risk of BC in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Plasma concentrations of folate and vitamin B12 were determined in 2,491 BC cases individually ...
    • Characterization of the degree of food processing in the European Prospective Investigation into Cancer and Nutrition: Application of the Nova classification and validation using selected biomarkers of food processing 

      Huybrechts, Inge; Rauber, Fernanda; Nicolas, Geneviève; Casagrande, Corinne; Kliemann, Nathalie; Wedekind, Roland; Biessy, Carine; Scalbert, Augustin; Touvier, Mathilde; Aleksandrova, Krasimira; Jakszyn, Paula; Skeie, Guri; Bajracharya, Rashmita; Boer, Jolanda M. A.; Borné, Yan; Chajes, Veronique; Dahm, Christina C.; Dansero, Lucia; Guevara, Marcela; Heath, Alicia K.; Ibsen, Daniel B.; Papier, Keren; Katzke, Verena; Kyrø, Cecilie; Masala, Giovanna; Molina-Montes, Esther; Robinson, Oliver J. K.; Santiuste de Pablos, Carmen; Schulze, Matthias B.; Simeon, Vittorio; Sonestedt, Emily; Tjønneland, Anne; Tumino, Rosario; van der Schouw, Yvonne T.; Verschuren, W. M. Monique; Vozar, Beatrice; Winkvist, Anna; Gunter, Marc J.; Monteiro, Carlos A.; Millett, Christopher; Levy, Renata Bertazzi (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-16)
      Background: Epidemiological studies have demonstrated an association between the degree of food processing in our diet and the risk of various chronic diseases. Much of this evidence is based on the international Nova classification system, which classifies food into four groups based on the type of processing: (1) Unprocessed and minimally processed foods, (2) Processed culinary ingredients, ...
    • Cigarette Smoking and Endometrial Cancer Risk: Observational and Mendelian Randomization Analyses 

      Dimou, Niki; Omiyale, Wemimo; Biessy, Carine; Viallon, Vivian; Kaaks, Rudolf; O'Mara, Tracy A.; Aglago, Elom K.; Ardanaz, Eva; Bergmann, Manuela M.; Bondonno, Nicola P.; Braaten, Tonje; Colorado-Yohar, Sandra M.; Crous-Bou, Marta; Dahm, Christina C.; Fortner, Renée T.; Gram, Inger Torhild; Harlid, Sophia; Heath, Alicia K.; Idahl, Annika; Kvaskoff, Marina; Nøst, Therese Haugdahl; Overvad, Kim; Palli, Domenico; Perez-Cornago, Aurora; Sacerdote, Carlotta; Sánchez, Maria-Jose; Schulze, Matthias B.; Severi, Gianluca; Simeon, Vittorio; Tagliabue, Giovanna; Tjønneland, Anne; Truong, Thérése; Tumino, Rosario; Johansson, Mattias; Weiderpass, Elisabete; Murphy, Neil; Gunter, Marc J.; Lacey, Ben; Allen, Naomi E.; Dossus, Laure (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-16)
      Background: Current epidemiologic evidence indicates that smoking is associated with a lower endometrial cancer risk. However, it is unknown if this association is causal or confounded. To further elucidate the role of smoking in endometrial cancer risk, we conducted complementary observational and Mendelian randomization (MR) analyses.<p> <p>Methods: The observational analyses included 286,415 ...
    • Circulating inflammatory biomarkers, adipokines and breast cancer risk—a case-control study nested within the EPIC cohort 

      Cairat, Manon; Rinaldi, Sabina; Navionis, Anne-Sophie; Romieu, Isabelle; Biessy, Carine; Viallon, Vivian; Olsen, Anja; Tjønneland, Anne; Fournier, Agnès; Severi, Gianluca; Kvaskoff, Marina; Fortner, Renée T.; Kaaks, Rudolf; Aleksandrova, Krasimira; Schulze, Matthias B.; Masala, Giovanna; Tumino, Rosario; Sieri, Sabina; Grasso, Chiara; Mattiello, Amalia; Gram, Inger Torhild; Olsen, Karina Standahl; Agudo, Antonio; Etxezarreta, Pilar Amiano; Sánchez, Maria-Jose; Santiuste, Carmen; Barricarte, Aurelio; Monninkhof, Evelyn; Hiensch, Anouk E.; Muller, David; Merritt, Melissa A.; Travis, Ruth C.; Gunter, Marc J.; Dossus, Laure; Weiderpass, Elisabete (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-18)
      Background: Infammation has been hypothesized to play a role in the development and progression of breast can‑ cer and might diferently impact breast cancer risk among pre and postmenopausal women. We performed a nested case-control study to examine whether pre-diagnostic circulating concentrations of adiponectin, leptin, c-reactive protein (CRP), tumour necrosis factor-α, interferon-γ and 6 ...
    • Dietary intake of trans fatty acids and breast cancer risk in 9 European countries 

      Matta, Michèle; Huybrechts, Inge; Biessy, Carine; Casagrande, Corinne; Yammine, Sahar; Fournier, Agnès; Olsen, Karina Standahl; Lukic, Marco; Gram, Inger Torhild; Ardanaz, Eva; Sánchez, Maria-José; Dossus, Laure; Fortner, Renée T.; Srour, Bernard; Jannasch, Franziska; Schulze, Matthias B.; Amiano, Pilar; Agudo, Antonio; Colorado-Yohar, Sandra; Guirós, J. Ramón; Tumino, Rosario; Panico, Salvatore; Masala, Giovanna; Pala, Valeria; Sacerdote, Carlotta; Tjønneland, Anne; Olsen, Anja; Dahm, Christina C.; Rosendahl, Ann H.; Borgquist, Signe; Wennberg, Maria; Heath, Alicia K.; Aune, Dagfinn; Schmidt, Julie; Weiderpass, Elisabete; Chajes, Veronique; Gunter, Marc J.; Murphy, Neil (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-30)
      Background - Trans fatty acids (TFAs) have been hypothesised to influence breast cancer risk. However, relatively few prospective studies have examined this relationship, and well-powered analyses according to hormone receptor-defined molecular subtypes, menopausal status, and body size have rarely been conducted.<p> <p>Methods - In the European Prospective Investigation into Cancer and Nutrition ...
    • Fiber intake modulates the association of alcohol intake with breast cancer 

      Romieu, Isabelle; Ferrari, Pietro; Chajès, Véronique; de Batlle, Jordi; Biessy, Carine; Scoccianti, Chiara; Dossus, Laure; Boutron, Marie Christine; Bastide, Nadia; Overvad, Kim; Olsen, Anja; Tjønneland, Anne; Kaaks, Rudolf; Boeing, Heiner; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; Palli, Domenico; Sieri, Sabina; Tumino, Rosario; Vineis, Paolo; Panico, Salvatore; Bueno-De-Mesquita, Hendrik Bastiaan; Gils, Carla H.; Peeters, Petra H.; Lund, Eiliv; Skeie, Guri; Weiderpass, Elisabete; Quirós, J Ramón; Chirlaque, Maria-Dolores; Ardanaz, Eva; Sánchez, María-José; Duell, Eric J.; Amiano Etxezarreta, Pilar; Borgquist, Signe; Hallmans, Göran; Johansson, Ingegerd; Nilsson, Lena Maria; Khaw, Kay-Tee; Wareham, Nick; Key, Timothy J.; Travis, Ruth C.; Murphy, Neil; Wark, Petra A.; Riboli, Elio (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-09-06)
      Alcohol intake has been related to an increased risk of breast cancer (BC) while dietary fiber intake has been inversely associated to BC risk. A beneficial effect of fibers on ethanol carcinogenesis through their impact on estrogen levels is still controversial. We investigated the role of dietary fiber as a modifying factor of the association of alcohol and BC using data from the European Prospective ...
    • Food biodiversity and total and cause-specific mortality in 9 European countries: An analysis of a prospective cohort study 

      Hanley-Cook, Giles T.; Huybrechts, Inge; Biessy, Carine; Remans, Roseline; Kennedy, Gina; Deschasaux-Tanguy, Mélanie; Murray, Kris A.; Touvier, Mathilde; Skeie, Guri; Kesse-Guyot, Emmanuelle; Argaw, Alemayehu; Casagrande, Corinne; Nicolas, Geneviève; Vineis, Paolo; Millett, Christopher J.; Weiderpass, Elisabete; Ferrari, Pietro; Dahm, Christina C.; Bueno-De-Mesquita, H. Bas; Sandanger, Torkjel M; Ibsen, Daniel B.; Freisling, Heinz; Ramne, Stina; Jannasch, Franziska; van der Schouw, Yvonne T.; Schulze, Matthias B.; Tsilidis, Konstantinos K.; Tjønneland, Anne; Ardanaz, Eva; Bodén, Stina; Cirera, Lluís; Gargano, Giuliana; Halkjær, Jytte; Jakszyn, Paula; Johansson, Ingegerd; Katzke, Verena; Masala, Giovanna; Panico, Salvatore; Rodriguez-Barranco, Miguel; Sacerdote, Carlotta; Srour, Bernard; Tumino, Rosario; Riboli, Elio; Gunter, Marc J.; Jones, Andrew D.; Lachat, Carl (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-18)
      Background<p> <p>Food biodiversity, encompassing the variety of plants, animals, and other organisms consumed as food and drink, has intrinsic potential to underpin diverse, nutritious diets and improve Earth system resilience. Dietary species richness (DSR), which is recommended as a crosscutting measure of food biodiversity, has been positively associated with the micronutrient adequacy of diets ...
    • Healthy lifestyle and risk of cancer in the European prospective investigation into cancer and nutrition cohort study 

      McKenzie, Fiona; Biessy, Carine; Ferrari, Pietro; Freisling, Heinz; Rinaldi, Sabina; Chajes, Veronique; Dahm, Christina C; Overvad, Kim; Dossus, Laure; Lagiou, Pagona; Trichopoulos, Dimitrios; Trichopoulou, Antonia; Bas Bueno-De-Mesquita, H; May, Anne; Peeters, Petra H; Weiderpass, Elisabete; Sanchez, Maria-Jose; Navarro, Carmen; Ardanaz, Eva; Ericson, Ulrica; Wirfalt, Elisabet; Travis, Ruth C; Romieu, Isabelle (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-04)
      It has been estimated that at least a third of the most common cancers are related to lifestyle and as such are preventable. Key modifiable lifestyle factors have been individually associated with cancer risk; however, less is known about the combined effects of these factors. This study generated a healthy lifestyle index score (HLIS) to investigate the joint effect of modifiable factors on ...
    • Metabolically Defined Body Size Phenotypes and Risk of Endometrial Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) 

      Kliemann, Nathalie; Ammar, Romain Ould; Biessy, Carine; Gicquiau, Audrey; Katzke, Verena; Kaaks, Rudolf; Tjønneland, Anne; Olsen, Anja; Sánchez, Maria-Jose; Crous-Bou, Marta; Pasanisi, Fabrizio; Tin, Sandar Tin; Perez-Cornago, Aurora; Aune, Dagfinn; Christakoudi, Sofia; Heath, Alicia K.; Colorado-Yohar, Sandra M.; Grioni, Sara; Skeie, Guri; Sartor, Hanna; Idahl, Annika; Rylander, Charlotta; May, Anne M.; Weiderpass, Elisabete; Freisling, Heinz; Playdon, Mary C.; Rinaldi, Sabina; Murphy, Neil; Huybrechts, Inge; Dossus, Laure; Gunter, Marc J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-01)
      Background: Obesity is a risk factor for endometrial cancer but whether metabolic dysfunction is associated with endometrial cancer independent of body size is not known.<p> <p>Methods: The association of metabolically defined body size phenotypes with endometrial cancer risk was investigated in a nested case–control study (817 cases/ 817 controls) within the European Prospective Investigation ...
    • Mycotoxin Exposure and Renal Cell Carcinoma Risk: An Association Study in the EPIC European Cohort 

      Claeys, Liesel; De Saeger, Sarah; Scelo, Ghislaine; Biessy, Carine; Casagrande, Corinne; Nicolas, Genevieve; Korenjak, Michael; Fervers, Beatrice; Heath, Alicia K.; Krogh, Vittorio; Luján-Barroso, Leila; Castilla, Jesús; Ljungberg, Börje; Rodriguez-Barranco, Miguel; Ericson, Ulrika; Santiuste, Carmen; Catalano, Alberto; Overvad, Kim; Brustad, Magritt; Gunter, Marc J.; Zavadil, Jiri; De Boevre, Marthe; Huybrechts, Inge (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-30)
      Background: Mycotoxins have been suggested to contribute to a spectrum of adverse health effects in humans, including at low concentrations. The recognition of these food contaminants being carcinogenic, as co-occurring rather than as singularly present, has emerged from recent research. The aim of this study was to assess the potential associations of single and multiple mycotoxin exposures with ...
    • Novel Biomarkers of Habitual Alcohol Intake and Associations With Risk of Pancreatic and Liver Cancers and Liver Disease Mortality 

      Loftfield, Erikka; Stepien, Magdalena; Viallon, Vivian; Trijsburg, Laura; Rothwell, Joseph A.; Robinot, Nivonirina; Biessy, Carine; Bergdahl, Ingvar A.; Bodén, Stina; Schulze, Matthias B.; Bergman, Manuela; Weiderpass, Elisabete; Schmidt, Julie A.; Zamora-Ros, Raúl; Nøst, Therese Haugdahl; Sandanger, Torkjel M; Sonestedt, Emily; Ohlsson, Bodil; Katzke, Verena; Kaaks, Rudolf; Ricceri, Fulvio; Tjønneland, Anne; Dahm, Christina C.; Sánchez, Maria-Jose; Trichopoulou, Antonia; Tumino, Rosario; Chirlaque, María-Dolores; Masala, Giovanna; Ardanaz, Eva; Vermeulen, Roel; Brennan, P; Albanes, Demetrius; Weinstein, Stephanie J.; Scalbert, Augustin; Freedman, Neal D.; Gunter, Marc; Jenab, Mazda; Sinha, Rashmi; Keski-Rahkonen, Pekka; Ferrari, Pietro (Preprint; Manuskript, 2021-05-19)
      Background - Alcohol is an established risk factor for several cancers, but modest alcohol-cancer associations may be missed because of measurement error in self-reported assessments. Biomarkers of habitual alcohol intake may provide novel insight into the relationship between alcohol and cancer risk.<p> <p>Methods - Untargeted metabolomics was used to identify metabolites correlated with ...
    • Nutritional quality of food as represented by the FSAm-NPS nutrient profiling system underlying the Nutri-Score label and cancer risk in Europe: Results from the EPIC prospective cohort study 

      Deschasaux, Mélanie; Huybrechts, Inge; Murphy, Neil; Julia, Chantal; Hercberg, Serge; Srour, Bernard; Kesse-Guyot, Emmanuelle; Latino-Martel, Paule; Biessy, Carine; Casagrande, Corinne; Jenab, Mazda; Ward, Heather; Weiderpass, Elisabete; Dahm, Christina C.; Overvad, Kim; Kyrø, Cecilie; Olsen, Anja; Affret, Aurélie; Boutron-Ruault, Marie-Christine; Mahamat-Saleh, Yahya; Kaaks, Rudolf; Kühn, Tilman; Boeing, Heiner; Schwingshackl, Lukas; Bamia, Christina; Peppa, Eleni; Trichopoulou, Antonia; Masala, Giovanna; Krogh, Vittorio; Panico, Salvatore; Tumino, Rosario; Sacerdote, Carlotta; Bueno-De-Mesquita, Hendrik Bastiaan; Peeters, Petra H.; Hjartåker, Anette; Rylander, Charlotta; Skeie, Guri; Ramõn Quirõs, Jose; Jakszyn, Paula; Salamanca-Fernández, Elena; Huerta, José María; Ardanaz, Eva; Amiano, Pilar; Ericson, Ulrika; Sonestedt, Emily; Huseinovic, Ena; Johansson, Ingegerd; Khaw, Kay-Tee; Wareham, Nick; Bradbury, Kathryn E.; Perez-Cornago, Aurora; Tsilidis, Konstantinos K.; Ferrari, Pietro; Riboli, Elio; Gunter, Mark J.; Touvier, Mathilde (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-18)
      <p><i>Background - </i>Helping consumers make healthier food choices is a key issue for the prevention of cancer and other diseases. In many countries, political authorities are considering the implementation of a simplified labelling system to reflect the nutritional quality of food products. The Nutri-Score, a five-colour nutrition label, is derived from the Nutrient Profiling System of the British ...
    • Plasma elaidic acid level as biomarker of industrial trans fatty acids and risk of weight change: Report from the EPIC study 

      Chajès, Véronique; Biessy, Carine; Ferrari, Pietro; Romieu, Isabelle; Freisling, Heinz; Huybrechts, Inge; Scalbert, Augustin; Bueno-de-Mesquita, H. Bas; Romaguera, Dora; Gunter, Mark J.; Vineis, Paolo; Hansen, Camilla Plambeck; Jakobsen, Marianne Uhre; Clavel-Chapelon, Françoise; Fagherazzi, Guy; Boutron-Ruault, Marie-Christine; Katzke, Verana; Neamat-Allah, Jasmine; Boeing, Heiner; Bachlechner, Ursula; Trichopoulou, Antonia; Naska, Androniki; Orfanos, Philippos; Pala, Valeria; Masala, Giovanna; Mattiello, Amalia; Skeie, Guri; Weiderpass, Elisabete; Agudo, Antonio; Huerta, José María; Sánchez, Mariá-José; Dorronsoro, Miren; Quirós, José Ramón; Johansson, Ingegerd; Winkvist, Anna; Sonested, Emily; Key, Timothy J.; Khaw, Kay-Tee; Wareham, Nicholas J.; Peeters, Petra H.M.; Slimani, Nadia (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-02-12)
      Background Few epidemiological studies have examined the association between dietary trans fatty acids and weight gain, and the evidence remains inconsistent. The main objective of the study was to investigate the prospective association between biomarker of industrial trans fatty acids and change in weight within the large study European Prospective Investigation into Cancer and Nutrition ...
    • Prediagnostic selenium status, selenoprotein gene variants and association with breast cancer risk in a European cohort study 

      Hughes, David J.; Schomburg, Lutz; Jenab, Mazda; Biessy, Carine; Méplan, Catherine; Moskal, Aurelie; Sun, Qian; Demircan, Kamil; Fedirko, Veronika; Weiderpass Vainio, Elisabete; Mukhtar, Maryam; Olsen, Anja; Tjønneland, Anne; Overvad, Kim; Schulze, Matthias; Nøst, Therese Haugdahl; Skeie, Guri; Olsen, Karina Standahl; Ricceri, Fulvio; Grioni, Sara; Palli, Domenico; Masala, Giovanna; Tumino, Rosario; Pasanisi, Fabrizio; Amiano, Pilar; Colorado Yohar, Sandra M.; Agudo, Antonio; Sánchez, Maria-Jose; Ardanaz, Eva; Sund, Malin; Andersson, Anne; Perez-Cornago, Aurora; Travis, Ruth; Heath, Alicia K.; Dossus, Laure (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-01)
      Selenium (Se) may help prevent breast cancer (BC) development. Owing to limited observational evidence, we investigated whether prediagnostic Se status and/or variants in the selenoprotein genes are associated with BC risk in a large European cohort. Se status was assessed by plasma measures of Se and its major circulating proteins, selenoprotein P (SELENOP) and glutathione peroxidase 3 (GPX3), in ...
    • Prospective analysis of circulating metabolites and endometrial cancer risk 

      Dossus, Laure; Kouloura, Eirini; Biessy, Carine; Viallon, Vivian; Siskos, Alexandros P.; Dimou, Niki; Rinaldi, Sabina; Merritt, Melissa A.; Allen, Naomi E.; Fortner, Renée T.; Kaaks, Rudolf; Weiderpass, Elisabete; Gram, Inger Torhild; Rothwell, Joseph A.; Lécuyer, Lucie; Severi, Gianluca; Schulze, Matthias B.; Nøst, Therese Haugdahl; Crous-Bou, Marta; Sánchez, Maria-Jose; Amiano, Pilar; Colorado-Yohar, Sandra; Barricarte, Aurelio; Schmidt, Julie A.; Palli, Domenico; Agnoli, Claudia; Tumino, Rosario; Sacerdote, Carlotta; Mattiello, Amalia; Vermeulen, Roel; Heath, Alicia K.; Christakoudi, Sofia; Tsilidis, Konstantinos K.; Travis, Ruth C.; Gunter, Marc J.; Keun, Hector C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-05)
      Background. Endometrial cancer is strongly associated with obesity and dysregulation of metabolic factors such as estrogen and insulin signaling are causal risk factors for this malignancy. To identify additional novel metabolic pathways associated with endometrial cancer we performed metabolomic analyses on pre-diagnostic plasma samples from 853 case-control pairs from the European Prospective ...
    • A prospective evaluation of plasma phospholipid fatty acids and breast cancer risk in the EPIC study 

      Chajès, Véronique; Assi, Nada; Biessy, Carine; Ferrari, P.; Rinaldi, Sabina; Slimani, Nadia; Lenoir, GM; Baglietto, L; His, Mathilde; Boutron-Ruault, M.C.; Trichopoulou, A; Lagiou, P.; Katsoulis, M; Kaaks, R.; Kuhn, T.; Panico, S.; Pala, V; Masala, G; Bueno-De-Mesquita, Hendrik Bastiaan; Peeters, P.H.; van Gils, Carla; Hjartåker, Anette; Olsen, Karina Standahl; Borgund Barnung, Runa; Barricarte, A; Redondo-Sánchez, Daniel; Menéndez, V; Amiano, P.; Wennberg, Maria; Key, T.; Khaw, K.T.; Merritt, M.A.; Riboli, E.; Gunter, M.J.; Romieu, I. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-09-18)
      <p><i>Background</i>: Intakes of specific fatty acids have been postulated to impact breast cancer risk but epidemiological data based on dietary questionnaires remain conflicting.</p> <p><i>Materials and methods</i>: We assessed the association between plasma phospholipid fatty acids and breast cancer risk in a case–control study nested within the European Prospective Investigation into Cancer ...
    • Sources of pre-analytical variations in yield of DNA extracted from blood samples: analysis of 50,000 DNA samples in EPIC 

      Caboux, Elodie; Lallemand, Christophe; Ferro, Gilles; Hemon, Bertrand; Mendy, Maimuna; Biessy, Carine; Sims, Matt; Wareham, Nicholas; Britten, Abigail; Boland, Anne; Hutchinson, Amy; Siddiq, Afshan; Vineis, Paolo; Riboli, Elio; Romieu, Isabelle; Rinaldi, Sabina; Gunter, Mark J.; Peeters, Petra H.M.; van der Schouw, Yvonne T.; Travis, Ruth C.; Bueno-De-Mesquita, H. Bas; Canzian, Federico; Sanchez, Maria-José; Skeie, Guri; Olsen, Karina Standahl; Lund, Eiliv; Bilbao, Roberto; Sala, Núria; Barricarte, Aurelio; Palli, Domenico; Navarro, Carmen; Panico, Salvatore; Redondo, Maria Luisa; Polidoro, Silvia; Dossus, Laure; Boutron-Ruault, Marie-Christine; Clavel-Chapelon, Françoise; Trichopoulou, Antonia; Trichopoulos, Dimitrios; Lagiou, Pagona; Boeing, Heiner; Fisher, Eva; Tumino, Rosario; Agnoli, Claudia; Hainaut, Pierre (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      The European Prospective Investigation into Cancer and nutrition (EPIC) is a long-term, multi-centric prospective study in Europe investigating the relationships between cancer and nutrition. This study has served as a basis for a number of Genome-Wide Association Studies (GWAS) and other types of genetic analyses. Over a period of 5 years, 52,256 EPIC DNA samples have been extracted using an automated ...
    • Ultra-processed foods, adiposity and risk of head and neck cancer and oesophageal adenocarcinoma in the European Prospective Investigation into Cancer and Nutrition study: a mediation analysis 

      Morales-Berstein, Fernanda; Biessy, Carine; Viallon, Vivian; Goncalves-Soares, Ana; Casagrande, Corinne; Hémon, Bertrand; Kliemann, Nathalie; Cairat, Manon; Blanco Lopez, Jessica; Al Nahas, Aline; Chang, Kiara; Vamos, Eszter; Rauber, Fernanda; Bertazzi Levy, Renata; Barbosa Cunha, Diana; Jakszyn, Paula; Ferrari, Pietro; Vineis, Paolo; Masala, Giovanna; Catalano, Alberto; Sonestedt, Emily; Borné, Yan; Katzke, Verena; Bajracharya, Rashmita; Agnoli, Claudia; Guevara, Marcela; Heath, Alicia; Radoï, Loredana; Mancini, Francesca; Weiderpass Vainio, Elisabete; Huerta, José María; Sánchez, María-José; Tjønneland, Anne; Kyrø, Cecilie; Schulze, Matthias B.; Skeie, Guri; Lukic, Marko; Braaten, Tonje Bjørndal; Gunter, Marc; Millett, Christopher; Agudo, Antonio; Brennan, Paul; Borges, M. Carolina; Richmond, Rebecca C.; Richardson, Tom G.; Davey Smith, George; Relton, Caroline L.; Huybrechts, Inge (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-22)
      Purpose - To investigate the role of adiposity in the associations between ultra-processed food (UPF) consumption and head and neck cancer (HNC) and oesophageal adenocarcinoma (OAC) in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.<p> <p>Methods - Our study included 450,111 EPIC participants. We used Cox regressions to investigate the associations between the ...